Developmental Evolution of Dendriti Morphology in a Multi-Compartmental Neuron Model
نویسنده
چکیده
منابع مشابه
Developmental Evolution of Dendritic Morphology in a Multi-Compartmental Neuron Model - Artificial Neural Networks, 1999. ICANN 99. Ninth International Conference on (Conf. Publ. No. 470
Through the use of a multi-compartmental neuron simulation, Mainen and Sejnowski demonstrated that spike generation in neurons is a function of their dendritic structure [l]. In this paper we investigate the determination of dendritic morphology given a desired set of spike traces. A genetic algorithm is used to identify optimal parameters for a developmental model which simulates the growth of...
متن کاملRole of transport performance on neuron cell morphology
The compartmental model is a basic tool for studying signal propagation in neurons, and, if the model parameters are adequately defined, it can also be of help in the study of electrical or fluid transport. Here we show that the input resistance, in different networks which simulate the passive properties of neurons, is the result of an interplay between the relevant conductances, morphology an...
متن کاملConstruction of anatomically correct models of mouse brain networks
The Mouse Brain Web, a federated database, provides for the construction of anatomically correct models of mouse brain networks. Each web page in this database provides the position, orientation, morphology, and putative synapses for each biologically observed neuron. The Mouse Brain Web has been designed to support (1) mapping of the spatial distribution and morphology of neurons by type; (2) ...
متن کاملAccelerating compartmental modeling on a graphical processing unit
Compartmental modeling is a widely used tool in neurophysiology but the detail and scope of such models is frequently limited by lack of computational resources. Here we implement compartmental modeling on low cost Graphical Processing Units (GPUs), which significantly increases simulation speed compared to NEURON. Testing two methods for solving the current diffusion equation system revealed w...
متن کاملA finite state automaton model for multi-neuron simulations
‘Classical’ compartmental modelling techniques involve numerical solution of large sets of ordinary differential equations (ODEs). The computational cost of neuronal network evaluation using these techniques forms a major bottleneck in the exploration of the effects of dendrite morphology on network functionality. To reduce computational load, we have developed a finite state automaton model of...
متن کامل